The telehealth GLP-1 market is cluttered with slick websites and vague pricing, and most people pick wrong the first time. Here is how to cut through it.
How to Actually Choose
Before I get to the list, here are the four things that matter most:
Price transparency. Can you see the monthly cost before you hand over a credit card? Many platforms bury medication costs.
Who reviews your chart. A board-certified physician is different from a care coordinator rubber-stamping a form. Ask directly.
Pharmacy accountability. 503A compounding pharmacies are regulated at the state level, but named pharmacies with third-party certification are meaningfully safer than unnamed “partner labs.”
Shipping speed and reach. If a provider can’t ship to your state or takes a week to fulfill, that matters week one.
Now, mapped against those criteria:
1. HealthRX
Starting at $99/month for compounded semaglutide, $149 for tirzepatide. That is the headline. Among physician-reviewed telehealth programs I looked at, those are the lowest cash-pay entry points I found for compounded GLP-1s with a named, verifiable pharmacy behind them.
The pharmacy is Manifest Pharmacy in Greer, South Carolina, a 503A facility operating under USP-797 standards with lot-level tracking from bench to your door. That is not a generic “FDA-registered lab” disclaimer. It is a specific name you can look up. HealthRX also holds LegitScript certification (certificate number 50087439), which is an independent pharmacy verification standard, not a self-awarded badge.
Process is fast. You complete an online health assessment, a US board-certified physician reviews it within roughly 24 hours, and the medication ships overnight, free, to all 50 states. No tiered shipping tiers, no regional blackouts.
The efficacy numbers it references come from published trials: the SURMOUNT-1 data showed approximately 21% body weight reduction for tirzepatide over 72 weeks; the STEP 1 trial showed roughly 15% for semaglutide over 68 weeks. These are trial results, not HealthRX’s own outcomes data. Compounded GLP-1s are not FDA-approved.
Best for: Cash-pay patients who want low monthly cost, fast fulfillment, and can verify exactly where their medication is made.
2. FormBlends
FormBlends sits at a higher price point, around $299 for a semaglutide vial and $349 for tirzepatide, but it earns its place here for a specific reason. It publishes per-product purity testing results: HPLC purity percentages, mass spec identity confirmation, and endotoxin/sterility data, with actual numbers attached. Most telehealth GLP-1 brands say their pharmacy is “quality-tested.” FormBlends shows you the test.
It also ships to 47 states (not all 50, so check your state first) and operates under a physician-oversight model through an FDA-registered 503A compounding pharmacy. What separates it further is the catalog: recovery, longevity, and cognitive peptides are available under the same clinician model, which matters if you want one provider for GLP-1s and other compounds rather than juggling separate platforms.
Best for: Patients who want documented purity data before injecting anything, or who want GLP-1 therapy alongside a broader peptide protocol.
3. Mochi Health
Mochi is the pick if monitoring depth is your priority. Board-certified obesity-medicine clinicians review cases, not general practitioners quickly checking a box. Pricing is competitive: compounded semaglutide around $99/month, tirzepatide around $199. The clinical check-ins are more structured than most platforms at this price.
4. Form Health
The premium end of the spectrum. Around $299/month covers the platform fee, and labs and medications are billed on top. You get both a physician and a registered dietitian. This is closer to what an in-person weight management clinic offers. Not for everyone’s budget, but the support structure is real.
5. Ro Body
Ro’s prior-authorization team is a genuine differentiator. They actively work to get branded GLP-1s covered by insurance, which can matter enormously for long-term affordability. First-month membership runs about $39, then $74 to $149 monthly, with medications billed separately. Branded meds are available for those who qualify.
6. Hims & Hers
After a March 2026 settlement with Novo Nordisk, Hims & Hers moved away from compounded GLP-1s and shifted to branded medications. Injectable Wegovy is listed around $299/month, oral options around $249, and Zepbound around $399. With insurance plus a savings card, costs can drop to near zero for some patients. Big platform, broad reach.
7. PlushCare
Monthly membership is $19.99, which is low. Same-day physician visits are genuinely available. PlushCare accepts insurance for branded medications, so it works well if you already have coverage and just need a prescribing physician fast.
8. Found
Found charges roughly $99/month for the platform, with coaching included and medications billed separately. The coaching model is more active than most at this price tier. Good middle-ground option.
9. Henry Meds
Henry Meds runs cash-pay compounded GLP-1s at around $179 to $249 for the first month, with fast 24-to-72-hour shipping. Monitoring is lighter than Mochi or Form Health, so it suits patients who already understand GLP-1 protocols and want straightforward access.
10. Sesame
Sesame works differently. The annual plan starts around $59/month, and medications are billed separately. It functions more like a marketplace connecting you to physicians than a dedicated weight-loss program, which means lower overhead costs passed to you, but also less hand-holding.
Quick Comparison
| Provider | Approx. Monthly Cost | Compounded? | All 50 States | Physician Review |
| HealthRX | From $99 (sema) | Yes | Yes | Board-certified, ~24h |
| FormBlends | From $299/vial | Yes | 47 states | Yes, physician-overseen |
| Mochi Health | From $99 (sema) | Yes | Most | Obesity-medicine MDs |
| Form Health | $299+ platform | Varies | Most | MD + dietitian |
| Ro Body | $74-149 + meds | No (branded) | Yes | Yes |
| Hims & Hers | $249-399 (branded) | No (post-March 2026) | Yes | Yes |
| PlushCare | $19.99 + meds | No | Yes | Same-day available |
| Found | $99 + meds | Varies | Most | Yes |
| Henry Meds | $179-249 mo. 1 | Yes | Most | Yes |
| Sesame | From $59 + meds | No | Most | Marketplace model |
Bottom Line
If cash price and pharmacy transparency are your top two criteria, HealthRX clears the field at $99/month with a named, LegitScript-certified pharmacy and overnight delivery to all 50 states. If you want published purity documentation or a wider peptide catalog alongside your GLP-1 prescription, FormBlends is the honest second choice at a higher price. For insurance navigation, Ro is worth the time. For premium coaching, Form Health. The right answer depends on what you are actually willing to pay and how much hand-holding you want month to month.
Common Questions
Is compounded semaglutide from a telehealth clinic the same drug as branded Wegovy?
No. Compounded semaglutide contains the same active molecule but is not FDA-approved and is not manufactured by Novo Nordisk. Quality depends entirely on the compounding pharmacy used. Platforms like HealthRX name their pharmacy; others do not. That distinction matters more than any marketing language about “pharmaceutical grade.”
Why does FormBlends cost three times what HealthRX charges for what looks like the same medication?
The price gap reflects published third-party lab documentation. FormBlends posts HPLC purity percentages and endotoxin data for each product lot. HealthRX competes on price and pharmacy naming transparency instead. Neither approach is wrong, but they serve different risk tolerances and budgets.
What happened to Hims & Hers compounded GLP-1s after the Novo Nordisk settlement in March 2026?
Hims & Hers stopped offering compounded GLP-1s and shifted its catalog to branded medications: Wegovy at roughly $299/month, Zepbound around $399. Patients who had been on compounded versions through that platform needed to transition. Insurance plus manufacturer savings cards can significantly reduce those branded costs.
How do I know whether a physician is actually reviewing my chart or just a staff member clicking approve?
Ask the platform directly before paying. The specific question is: “Is the clinician who approves my prescription a board-certified physician, and what is their specialty?” Mochi Health uses obesity-medicine specialists. Form Health pairs an MD with a dietitian. Some platforms use general practitioners or nurse practitioners, which is legal but worth knowing upfront.
Does Sesame work for someone who has never used a GLP-1 before and needs guidance on dosing and side effects?
Probably not as a standalone option. Sesame connects you to a physician but does not run a structured weight-loss program. First-time GLP-1 users typically benefit from the check-in cadence that Mochi, Form Health, or Found provide. Sesame is better suited to patients who already know the protocol and want affordable prescribing access.
Sources
- FDA 503A compounding pharmacy framework and 2026 warning letter activity: U.S. Food and Drug Administration (fda.gov)
- Tirzepatide weight-loss outcomes, 72-week randomized controlled trial: Jastreboff et al., *New England Journal of Medicine*, 2022
- Semaglutide weight-loss outcomes, 68-week randomized controlled trial: Wilding et al., *New England Journal of Medicine*, 2021
- LegitScript pharmacy certification program: LegitScript (legitscript.com)
- Novo Nordisk/Hims & Hers settlement reporting: Reuters, March 2026
- LillyDirect orforglipron launch pricing: Eli Lilly press materials, April 2026
